The International Potato Center (CIP) has had an evolving research-for-development agenda that includes potatoes, sweet potatoes, Andean roots and tubers, and sustainable use of natural resources in mountains. In 2003, CIP completed a participatory Vision Exercise that led to prioritization of 7 development challenges that reflect 8 of the UN Millennium Development Goals (MDGs). In summary, these challenges include: reducing poverty and hunger; improving human health; developing sustainable rural and urban systems; and improving the availability of new technologies. A strategy was developed to help accomplish the selected MDGs. The first step towards implementation of this vision was a realignment of CIP's research program. Then, using different tools such as GIS and available national, regional, and world statistics, poverty targeting was carried out in order to prioritize the countries and regions where CIP will focus its resources and its research and development efforts. Targets were identified by overlaying poverty, hunger, and vulnerability with the areas where CIP's commodities are produced. Within this framework, the Center is implementing a new project in the Central Andes Altiplano, which is supported by the Government of Canada as well as other donors. The project is called ALTAGRO (Andean Agriculture in the Altiplano).