Title
Effect of aqueous extract from Piper elongatum vahl (Matico) on the intestinal motility in mice
Other title
[Efecto del extracto acuoso de Piper elongatum Vahl. (matico) sobre la motilidad intestinal en ratones]
Date Issued
01 January 2016
Access level
metadata only access
Resource Type
journal article
Author(s)
Verastegui-Díaz A.
Flores-Pariona E.
Carbajal-Rivera A.
Robles-Esquerre M.
Publisher(s)
Editorial Ciencias Medicas
Abstract
Objective: to evaluate the effect of aqueous extract from Piper elongatum Vahl (matico) on the intestinal motility in BALB/c mice. Methods: experimental study that used activated carbon. The involved groups were: Group 1 with negative control with 90/00NaCl; Group 2 positive control with loperamide 10mg/Kg, groups treated with the plant at doses of 125 mg/kg (Group3), 250 mg/kg (Group4) and 500 mg/Kg (Group5). ShapiroWilk, ANOVA and Bonferroni statistical tests were used; p<0.05 was considered as significant and 95 % confidence interval. Results: the percentages of intestine explored with the active charcoal were 69.4±4.5; 24.9±3.0; 75.3±4.3; 71.1±4.5; 56.4±2.7 and 59.4±3.0 in groups 1 to 5 respectively. The ANOVA on this variable showed a p<0,001. The post hoc Bonferroni test showed no differences between the negative control and treatment groups with Piper elongatum Vahl whereas there was a difference between the positive control and the other groups and between the groups 3 and 5 (p<0.001). Conclusions: the aqueous extract from Piper elongatum Vahl has no effect on the intestinal motility at the evaluated doses, so further studies are needed.
Start page
117
End page
126
Volume
50
Issue
1
Language
Spanish
OCDE Knowledge area
Gastroenterología, Hepatología
Otras ciencias médicas
Subjects
Scopus EID
2-s2.0-85016833073
Source
Revista Cubana de Farmacia
ISSN of the container
00347515
Sources of information:
Directorio de Producción Científica
Scopus