Title
Transforming growth factor β1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans
Date Issued
14 September 2000
Access level
open access
Resource Type
journal article
Author(s)
Robinson P.
Okhuysen P.C.
Chappell C.L.
Lewis D.E.
Shahab I.
Lahoti S.
Baylor College of Medicine
Publisher(s)
American Society for Microbiology
Abstract
Biopsies from volunteers challenged with Cryptosporidium parvum were examined for transforming growth factor β1 (TGF-β1). None of the prechallenge biopsies exhibited TGF-β. Seven of 12 volunteers with oocyst shedding expressed TGF-β versus 2 of 13 volunteers without detected oocysts. The association of TGF-β expression with oocyst excretion and the timing of symptoms suggests that TGF-β mediates intestinal healing.
Start page
5405
End page
5407
Volume
68
Issue
9
Language
English
OCDE Knowledge area
Inmunología Enfermedades infecciosas
Scopus EID
2-s2.0-0033863459
PubMed ID
Source
Infection and Immunity
ISSN of the container
00199567
Sources of information: Directorio de Producción Científica Scopus