The aim of this study was determine the mainly parameters from urine analysis providence of confirmed cases of Guinea pigs with cervical lymphadenitis. The study was realized in Cajamarca department and urine samples from 25 Guinea pigs with cervical lymphadenitis were collected, which were processed through manual method to evaluate physical, chemical parameters and urine sediment. The results of caseous lymphadenitis didn't present differences in comparison to the control animals (p>0.05), being the most commonly found findings the increased density (> 1.040), proteinuria (traces to 3+) and variable presence of crystals. It is conclude that, despite macroscopic lesions reported for this disease, including urinary tract and blood lesions, the absence of changes in the urine parameters of the affected animals suggests the chronicity of the development of the disease in Guinea pigs and the modulation to the development of pathologies that are reflected in changes in the analysis and perhaps in other laboratory tests that could be evaluated during the disease.