Title
Publication and associated factors of clinical trials registered in Peru
Date Issued
01 November 2020
Access level
metadata only access
Resource Type
journal article
Publisher(s)
Blackwell Publishing
Abstract
Objective: We aim to determine the percentage of publication and its associated factors of clinical trials (CTs) registered in Peru. Methods: Using a cross-sectional study design, we assessed CTs registered at the CT's Peruvian Registry (REPEC) during the 2011-2016 period, and evaluated its percentage of publication and associated factors. We used a bibliographic search algorithm to determine if the CTs were published and assessed the associated factors by using a Cox regression to estimate the adjusted hazard ratios (aHR) as the magnitude of association of interest. Results: We analyzed 228 CTs, of which 63% were published. The regression analysis identified the year of registration (aHR 2012 = 1.15 [0.58-2.27]; aHR 2013 = 0.45 [0.21-0.95]; aHR 2014 = 0.89 [0.43-1.82]; aHR 2015-2016 = 0.16 [0.05-0.58]), total number of participants (aHR = 1.12; 1.05-1.18), and phase III-IV (aHR = 2.15; 0.1.16-4.03) as factors associated with the publication of the CTs. Conclusions: The percentage of publication of CTs executed in Peru is insufficient, and it increases the older the year of its registration in the REPEC, mayor of the number of participating countries, and if it is a phase III or IV study.
Start page
284
End page
291
Volume
13
Issue
4
Language
English
OCDE Knowledge area
Ciencias socio biomédicas (planificación familiar, salud sexual, efectos políticos y sociales de la investigación biomédica)
Scopus EID
2-s2.0-85092139268
PubMed ID
Source
Journal of Evidence-Based Medicine
ISSN of the container
17565383
Sources of information: Directorio de Producción Científica Scopus