This research note proposes hypotheses and frameworks for the study of the dynamics of the German and French medical and scientific movement aimed at Latin America, and Brazil in particular, between 1919 and 1942. It also seeks to comprehend to what extent the efforts at intellectual cooperation and the concomitant flow of ideas, institutional models, common research agendas, and action strategies aimed at expanding the Franco-Germanic field of influence in this part of the American continent, were put into practice.