cris.boxmetadata.label.title
Porcine cysticercosis: Possible cross-reactivity of taenia hydatigena to GP50 antigen in the enzyme-linked immunoelectrotransfer blot assay
cris.boxmetadata.label.dateissued
01 browse.startsWith.months.january 2017
cris.boxmetadata.label.accesslevel
open access
cris.boxmetadata.label.resourcetype
journal article
cris.boxmetadata.label.authors
Muro C.
Gomez-Puerta L.
Flecker R.
Barreto P.
Dorny P.
Tsang V.
GONZALEZ ZARIQUIEY, ARMANDO EMILIANO
GARCIA LESCANO, HECTOR HUGO
O'Neal S.
cris.boxmetadata.label.publisher
American Society of Tropical Medicine and Hygiene
cris.boxmetadata.label.abstract
The lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB, reported sensitivity 99% and specificity 100%) is used as a serologic marker of exposure to Taenia solium in pigs. However, only a limited number of parasites have been evaluated for cross reactivity. Pigs may host other related cestode infections, including Taenia hydatigena, which have not been formally evaluated for cross-reactions.Weinvestigated a corral in Tumbes, Peru, a region where a cysticercosis elimination demonstration project was completed in 2012. In this corral, 14/19 (73.7%) 6-8-week-old piglets were reactive to GP50 on LLGP EITB, and all had circulating Taenia sp. antigens. From eight necropsied piglets; four were infected with T. hydatigenametacestodes whereas none had evidence of T. solium infection. Two resident dogs were subsequently confirmed to have T. hydatigena taeniasis. These results suggest GP50 crossreactivity in T. hydatigena-infected pigs, although controlled experimental infection is needed to confirm this hypothesis.
cris.boxmetadata.label.citationstartpage
1830
cris.boxmetadata.label.citationendpage
1832
cris.boxmetadata.label.volume
97
cris.boxmetadata.label.issue
6
cris.boxmetadata.label.language
English
cris.boxmetadata.label.ocdeknowledgeArea
Parasitología
cris.boxmetadata.label.doi
cris.boxmetadata.label.scopusidentifier
2-s2.0-85037041882
cris.boxmetadata.label.pubmedidentifier
cris.boxmetadata.label.source
American Journal of Tropical Medicine and Hygiene
cris.boxmetadata.label.containerissn
00029637
cris.boxmetadata.label.sponsor
Financial support: This research was made possible with support from the Fogarty International Center (FIC) and the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) grant number R21AI119438. Partial support from Training grant TW001140 from the Fogarty International Center in training of study team members is also acknowledged. National Institute of Allergy and Infectious Diseases R21AI119439 National Institute of Neurological Disorders and Stroke R01NS080645 Medical Research Council MR/K007467/1
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