Title
Functional remediation in bipolar disorder: 1-year follow-up of neurocognitive and functional outcome
Date Issued
01 January 2016
Access level
open access
Resource Type
journal article
Author(s)
Bonnin C.M.
Torrent C.
Arango C.
Amann B.L.
Solé B.
González-Pinto A.
Crespo J.M.
Tabarés-Seisdedos R.
Reinares M.
Ayuso-Mateos J.L.
García-Portilla M.P.
Ibañez
Salamero M.
Vieta E.
Martinez-Aran A.
Al-Halabi S.
Alonso-Lana S.
Anaya C.
Valle J.
Balanzá-Martínez V.
Colom F.
Barbeito S.
Bobes J.
Calvo A.
Cerrillo E.
Correa P.
Custal N.
Fernández P.
Fernández M.
Fuentes-Durá I.
Galván G.
Isella S.
Landín-Romero R.
Mayoral M.
Menchón J.
Merchan-Naranjo J.
Jiménez E.
Ortiz-Gil J.
Pacchiarotti I.
Rosa A.R.
Rapado-Castro M.
Rodao J.M.
Saiz P.A.
Sánchez-Moreno J.
Segura B.
Selva G.
Saiz-Ruiz J.
Subirá M.
Torres I.
Ugarte A.
Vega P.
Universidad de Barcelona
Publisher(s)
Cambridge University Press
Abstract
Background: Few randomised clinical trials have examined the efficacy of an intervention aimed at improving psychosocial functioning in bipolar disorder. Aims: To examine changes in psychosocial functioning in a group that has been enrolled in a functional remediation programme 1 year after baseline. Method: This was a multicentre, randomised, rater-masked clinical trial comparing three patient groups: functional remediation, psychoeducation and treatment as usual over 1-year follow-up. The primary outcome was change in psychosocial functioning measured by means of the Functioning Assessment Short Test (FAST). Group6time effects for overall psychosocial functioning were examined using repeated-measures ANOVA (trial registration NCT01370668). Results: There was a significant group6time interaction for overall psychosocial functioning, favouring patients in the functional remediation group (F = 3.071, d.f. = 2, P = 0.049). Conclusions: Improvement in psychosocial functioning is maintained after 1-year follow-up in patients with bipolar disorder receiving functional remediation.
Start page
87
End page
93
Volume
208
Issue
1
Language
English
OCDE Knowledge area
Psiquiatría
Scopus EID
2-s2.0-84956651406
PubMed ID
Source
British Journal of Psychiatry
ISSN of the container
00071250
Sources of information: Directorio de Producción Científica Scopus