Title
In silico analysis of transferable QepA variants and related chromosomal efflux pumps
Other title
Análisis in silico de variantes transferibles de QepA y de bombas cromosomales de eflujo relacionadas
Date Issued
01 December 2018
Access level
metadata only access
Resource Type
journal article
Author(s)
Universitat Autònoma de Barcelona
Publisher(s)
Sociedad Espanola de Quiminoterapia
Abstract
Objectives. The present study aimed to detect the presence of undescribed QepA variants in GenBank records. Material and methods. The DNA and amino acid sequences of QepA1 were compared with what is present in GenBank. Only annealings with a >80% identity were considered. No synthetic or partial sequences were included in the analyses. Results. The results showed the presence of 10 different QepA variants, 6 of them which were previously non-des-ignated as specific allelic variants. In addition, high identity levels with chromosomal MSF efflux pumps belonging to microorganisms of the Pseudorhodoferax genus and other Comamonadaceae were detected. Conclusions. The presence of undescribed QepA variants in GenBank is reported and the presence of related sequences among members of Burkholderiales order is described.
Start page
537
End page
541
Volume
31
Issue
6
Language
English
OCDE Knowledge area
Genética humana
Biología celular, Microbiología
Subjects
Scopus EID
2-s2.0-85056626047
PubMed ID
Source
Revista Espanola de Quimioterapia
ISSN of the container
02143429
Sources of information:
Directorio de Producción Científica
Scopus