Title
Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: A preliminary report
Date Issued
01 March 2018
Access level
open access
Resource Type
journal article
Author(s)
Publisher(s)
Sociedade Brasileira de Medicina Tropical
Abstract
Introduction: The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. Methods: In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. Results: Fas2-ELISA demonstrated negative results in all HCC patients included in this study. Conclusions: The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.
Start page
231
End page
233
Volume
51
Issue
2
Language
English
OCDE Knowledge area
Medicina tropical
Oncología
Gastroenterología, Hepatología
Subjects
Scopus EID
2-s2.0-85047012774
PubMed ID
Source
Revista da Sociedade Brasileira de Medicina Tropical
ISSN of the container
00378682
Sponsor(s)
Funding text 1
This study was approved by the Institutional Ethics Committee of UPCH under the approval ID 650516 and by the Human Subjects Committee of The Instituto de Enfermedades Neoplasicas (INEN) under the approval ID 113-2014-Comit Institucional de Etica (CIE)/INEN.
Funding text 2
This work was supported by the Third Cancer Plan of the French National Alliance for Life Sciences and Health (ENV201408) and by the Young Research Teams Associated with IRD Program (JEAI-INCAncer).
Sources of information:
Directorio de Producción Científica
Scopus