Title
Cordiosides A and B, two new 19-hydroxy-29-norlanostane glycosides isolated from the flowers of Cordia lutea
Date Issued
01 December 2022
Access level
open access
Resource Type
journal article
Author(s)
Castro Dionicio I.Y.
Fabre N.
Saffon-Merceron N.
Jullian V.
Publisher(s)
Elsevier Ltd
Abstract
We present here the isolation and structural characterization of two undescribed mono-glycosylated triterpenes with a 19-hydroxy-29-norlanostane core. These compounds (1-2) were isolated from an ethanolic extract of the dried flowers of Cordia lutea, a widely used Peruvian traditional medicine. Their structures were determined by examination of their NMR and MS data. For compound 1, its structure was confirmed by single crystal X-ray structural analyses. 1 showed moderate activity against Helicobacter pylori (MIC = 15.6 µg/mL), and was not active against Escherichia coli, Pseudomonas aeruginosa or Staphylococcus aureus (MIC > 125 µg/mL).
Start page
40
End page
44
Volume
52
Language
English
OCDE Knowledge area
Farmacología, Farmacia
Ciencias de las plantas, Botánica
Subjects
Scopus EID
2-s2.0-85138032140
Source
Phytochemistry Letters
ISSN of the container
18743900
Sponsor(s)
IC thanks the Institut de Recherche pour le Développement of France ( IRD ) for the award of a grant (Allocation de Recherche pour une Thèse au Sud, ARTS), and the Peruvian Council of Science ( CONCYTEC ) for previous funding. This work also benefited from the funding of the LMI LAVI (International joint Laboratory, IRD-UPCH) by the IRD. These sources of funding had no role in study design; collection, analysis and interpretation of data; writing of the report; and the decision to submit the article for publication.
Sources of information:
Directorio de Producción Científica
Scopus