The objective of the research was to verify the water quality and bioaccumulation of mining pollutants in tissues of Oncorhynchus mykiss “rainbow trout” in the Sicra, Opamayo and fish farm of Ocopa Lircay Huancavelica rivers. Sampling points were located, collecting water and trout samples. Incineration and digestion were performed; analyzing with the atomic absorption spectrophotometer; whose results for water samples in Sicra were: arsenic, cadmium and lead with-0.7711,-0.0021 and 0.0690 mg / l; in Opamayo-1.1508, 0.0016 and 0.0474 mg / l and Ocopa fish farm-1.2375,-0.0003 and 0.0252 mg / l respectively. Most of the values are below the maximum permissible PML limits, except for the lead in Sicra was 0.0690 mg / l, exceeding the PML, compared to Supreme Decree No. 015-2015-MINAM is 0.05mg / l. In Sicra trout, the Pb content in viscera was 1.4061 mg / kg and fish farm samples in skin was 4.5184 mg / kg; results that exceed the LMP according to the National Fisheries Health Agency SANIPES and the EUROPEAN UNION, which is 0.3 mg / kg. The Pearson R Statistic P> 0.05 validates the hypothesis, being the correlation of metalloid content and metals between water and trout, it results between 0.023 and 0.844, meaning a positive value. Concluding that water contamination had an impact on the trout, consequently the water quality is not optimal, evidencing the impact of mining origin.