To optimize the drilling and blasting process in underground mining using the Holmberg method to create the drilling-and-blasting mesh design. The method it is an experimental applied-type and correlational-level inductive method. The Holmberg method showed good efficiency of 95% because it works with the rock mass and volatility-index parameters of the rock. The total drilling and blasting time with the Holmberg method is 2 h, whereas with the traditional method it will be 8 h because the blasting will not be efficient and there will be an increase in the amount of cutting and/or drilling time. The total cost of the drilling and blasting process in the Holmberg method is 2143.85 soles, while with the traditional method, it is 2820.75 soles, without taking into account the loss and shutdown of production that this would cause.