Objective. Characterize the global scientific production on the vaccine to combat Covid-19 in the Scopus, Web of Science, Google Academic, PubMed, Microsoft Academic and Crosreff databases between the months of January 2020 to April 2021. Material and methods. We worked with a universe made up of 3817 articles obtained. Bibliometric indicators were calcu- lated through Publish or Perish v. 7.31, VOSwiever, Pubrem- iner, Dimensions and the same analytical software from the chosen databases. Results. The results indicate a total of 30619 citations, with an average of 5103; 11 and 2251 cita- tions per year, citations per article and citations per author re- spectively. On average, publications have an h-index of 26.00, a g-index of 42.00, and an e-index of 33.59. Prompetchara’s study, Eakachai; Kettoy, Chutitorn; Palaga, Tanapat, (2020), the British Medical Journal - BMJ, USA is the main producer of scientific evidence on vaccines and the type of scientific production that stands out the most are original articles. Con- clusions. These results show that the production of scientific articles on the vaccine to combat Covid-19 has experienced significant growth, which shows the enormous scientific effort made worldwide to control this disease.