We describe the case of a 35-year-old patient, who experienced preeclampsia and oliguric acute renal injury during her last pregnancy, requiring intervention by emergency cesarean section and dialysis support with a total of 16 hemodialysis sessions; she responded favorably. Four months after discharge, she developed nephrotic syndrome, so she was hospitalized for better management and a thorough etiologic research. Support measures were taken with no need for renal replacement therapy; secondary lesions were ruled out and a renal biopsy was performed. The pathological study concluded that it was a focal segmental glomerulosclerosis, in its perihilar variant. The patient responded favorably during her hospitalization and when discharged, she was summoned to continue management by external consultation. The appearance of nephrotic syndrome months after pregnancy may suggest the presence of an underlying glomerulopathy or de novo glomerulopathy.