Objectives: to evaluate the quality of prescriptions' filling in Independencia's District public health facilities in the department of Lima as a barrier to provide pharmaceutical care to patients. Materials and methods: It was carried out a cross-sectional study with prescriptions from the outpatients pharmacies of all the Independencia's District health facilities (11). During the month of November 2013, 384 prescriptions that have been assisted in October were randomly selected of each of the health facilities. Results: 384 prescriptions were randomly selected of each of the 11 health facilities which represented a whole of 4224 prescriptions. 24% of the prescriptions recorded the patient's weight (IC: 22,76%-25,30%); 34,2% included the diagnosis (IC: 32,80%- 35,62%); 93,7% included drugs expressed in INN (IC: 93,00-94,41%). Furthermore, only 11,3 mentioned the route of administration (IC: 10,40%-12,28%) and 41,4 pointed out the frequency (IC: 39,94%-42,88%). The length of treatment was missing in 32% of the evaluated prescriptions (IC: 66,62%-69,41%) and only 5,7 included the expiration date (IC: 5,00%-6,41%). These errors are barriers for the pharmaceutical care due to the fact that they make difficult the detection of problems related to drugs; on the other hand, they limit the information that can be given to a patient about the use of his/her drugs. Conclusion: Innovative strategies are needed in order to improve prescriptions so that they are not a barrier any more for the detection, solution and prevention of problems related to drugs.