Human infertility is considered a serious disease of the reproductive system that affects more than 10% of couples worldwide, and more than 30% of reported cases are related to men. The crucial step in evaluating male infertility is a semen analysis, highly dependent on sperm morphology. However, this analysis is done at the laboratory manually and depends mainly on the doctor's experience. Besides, it is laborious, and there is also a high degree of interlaboratory variability in the results. This article proposes applying a specialized convolutional neural network architecture (U-Net), which focuses on the segmentation of sperm cells in micrographs to overcome these problems. The results showed high scores for the model segmentation metrics such as precision (93%), IoU score (88%), and DICE score of 94%. Moreover, we can conclude that U-net architecture turned out to be a good option to carry out the segmentation of sperm cells.