Title
Safety, immunogenicity, and excretion pattern of single-dose live oral cholera vaccine CVD 103-HgR in Peruvian adults of high and low socioeconomic levels
Date Issued
01 January 1993
Access level
open access
Resource Type
editorial
Author(s)
Butron B.
Ruiz R.
Losonsky G.
Wasserman S.S.
Salazar E.
Kaper J.B.
Cryz S.
Levine M.M.
Publisher(s)
American Society for Microbiology
Abstract
Groups of 122 Peruvian adults of low socioeconomic level (SEL) and 125 of high SEL received a randomly allocated 5 x 109- or 5 x 108-CFU dose of CVD 103-HgR live oral cholera vaccine or a placebo. The vaccine was well tolerated. Vibriocidal seroconversions occurred in 78% of high-SEL and 72% of low-SEL subjects who ingested the high dose and in 78 and 49%, respectively, of those who received the low dose.
Start page
3994
End page
3997
Volume
61
Issue
9
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Otras ciencias médicas
Scopus EID
2-s2.0-0027304310
PubMed ID
Source
Infection and Immunity
ISSN of the container
00199567
Sponsor(s)
National Institute of Allergy and Infectious Diseases (N01AI062528)
Sources of information:
Directorio de Producción CientÃfica
Scopus