Title
Characterization of an integron carrying a new class D β-lactamase (OXA-37) in Acinetobacter baumannii
Date Issued
01 January 2002
Access level
metadata only access
Resource Type
journal article
Author(s)
Navia M.M.
Vila J.
Universitat de Barcelona
Publisher(s)
Mary Ann Liebert Inc.
Abstract
Integrons from a clinical strain of Acinetobacter baumannii highly resistant to β-lactams have been analyzed. The largest (2.2 kb) contained three gene cassettes: an aacA4, an open reading frame of 417 nucleotides, and an OXA-type encoding gene. The oxa gene nucleotide sequence differed from that of the oxa-20 in 2 bp, one of the mutations being silent. The nonsilent mutation generated a substitution of glutamic acid for aspartic acid. The new OXA has been named OXA-37.
Start page
261
End page
265
Volume
8
Issue
4
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Scopus EID
2-s2.0-0036929877
PubMed ID
Source
Microbial Drug Resistance
ISSN of the container
10766294
Sources of information: Directorio de Producción Científica Scopus