The aim of this article is to know the attitude of university students towards e-learning having age and gender as sociodemographic variables. It describes important aspects about virtual education, connectivism, e-learning model and factors about attitude towards e-learning, b-learning and its advantages. In this basic, descriptive level study, the scale of attitudes towards e-learning proposed by Mehra and Omidian (2012) consisting of 92 items (distributed on a dichotomous yes/no scale) was used, with a reliability, through Kr-20, of 0.995. The sample comprised a total of 330 medical students from a private university from the first to the fifth cycle of the degree. It was demonstrated that e-learning is a tool at the service of the teaching-learning processes that seeks interaction between the teacher and the student, developing cognitive, collaborative and self-regulatory skills in the university student. The conclusions of the research were that, regarding the sex of the students, 38.5% of the women perceived an unfavorable level and 34.2% of the men, a favorable level of attitude towards elearning. As for the intervening variable age, 23% of the students fewer than 21 years of age perceived an unfavorable level of attitude towards e-learning. In the ease of use dimension, 44.4% of the students perceived an unfavorable level. Finally, 40.3% perceived an unfavorable level; 34.8% perceived a fair level and 24.8% a favorable level of attitude towards e-learning.