Title
Characterization of a candidate locus for malaria susceptibility in human populations: A (TA)n microsatellite in the promoter region of the CYBB gene, the gp91phox subunit of the NADPH oxidase
Date Issued
01 April 2008
Access level
metadata only access
Resource Type
journal article
Author(s)
Universidade Federal de Minas Gerais
Publisher(s)
Wiley-Blackwell
Abstract
We have analysed the linkage disequilibrium pattern between the promoter TA microsatellite and Single Nucleotide Polymorphism (SNP) haplotypes for the CYBB gene. None of the CYBB SNPs serve as good surrogates for the microsatellite alleles, previously associated with mild malaria. Thus, the candidate (TA) n microsatellite should be directly tested in genetic epidemiology studies.
Start page
107
End page
109
Volume
35
Issue
2
Language
English
OCDE Knowledge area
Inmunología
Scopus EID
2-s2.0-40449140531
PubMed ID
Source
International Journal of Immunogenetics
ISSN of the container
1744313X
Sources of information:
Directorio de Producción Científica
Scopus