Introduction: Pregnancy generates physiological, hormonal, and psychic changes that affect sexuality. Objective: To determine the factors associated with sexuality during gestation and to show the changes in each trimester. Methodology: Transversal, analytical study, showing 346 postpartum women. A questionnaire of 47 items was applied: sociodemographic data, beliefs, experience, and information received about sexuality. Results: 56% had sexual encounters one month before delivery. Frequency of sexual encounters: once a week (54%, 43%, and 63% first, second, and third trimesters, respectively). The multivariate analysis was associated with women reporting greater sexual pleasure when they received information from the doctor or obstetrician (p<0.001 value), when reaching orgasm moderately easily (p<0.001) and when being stimulated in erogenous zones (p<0.001); on the contrary, those who experienced less sexual pleasure, were those who felt that sexual desire changed during pregnancy (p=0.020) and when they stimulated their partner in erogenous zones (p<0.001). Conclusions: The experience of sexuality changes during gestation. The information, the achievement of orgasm and stimulation in erogenous zones produce greater sexual pleasure.