Introduction: Native communities are one of the most forgotten human groups where inequities and inequalities in oral health are exacerbated. Objective: To determine the epidemiological and clinical profile of oral health in residents of the native communities of Potsoteni, Boca Sanibeni and Union Puerto Ashaninka of Mazamari district, Satipo province, Junín department, Peru. Material and Methods: A cross-sectional descriptive observational study was conducted. The sample consisted of 169 adults from native communities who fulfilled inclusion and exclusion criteria, following the ethical norms in scientific research. Oral health was evaluated through an epidemiological fact sheet with the following indicators: DMFT index, Significant Caries Index (SCI), simplified oral hygiene index (OHI-S), prosthetic need WHO index, classification of Angle malocclusion, and index of clinical consequences of untreated dental caries (PUFA). The evaluation was made with natural light by calibrated observers. The data was analyzed in the STATA v 14 program by means of frequency and figure distribution tables. Results: It was determined that 100% of the patients studied had dental caries (DMFT = 13.23, SCI = 19.01), OHI-S: 5.02 (SD = 0.51), the majority of them presented a type of malocclusion and clinical consequences of untreated caries; 116 (68.63%) and 115 (68%), respectively. The unitary dental prosthesis was the most needed in both jaws. Conclusions: The state of oral health was worrisome; it is necessary to promote policies that allow better access to health services in order to revert these indicators.