cris.boxmetadata.label.title
Kinetics and avidity of anti-toxocara antibodies (IgG) in rabbits experimentally infected with toxocara canis
cris.boxmetadata.label.dateissued
01 browse.startsWith.months.january 2016
cris.boxmetadata.label.accesslevel
open access
cris.boxmetadata.label.resourcetype
journal article
cris.boxmetadata.label.authors
Bin L.
Santarém V.
Laposy C.
Rubinsky-Elefant G.
ROLDAN GONZALES, WILLIAM HENRY
Giuffrida R.
Universidad de São Paulo
cris.boxmetadata.label.publisher
Brazilain Coll Veterinary Parasitology
cris.boxmetadata.label.abstract
An evaluation was made of the kinetics and avidity of anti-Toxocara antibodies (IgG) in rabbits experimentally infected with embryonated Toxocara canis eggs. Seventeen four month old New Zealand White rabbits were distributed into two groups. In the experimental group, twelve rabbits were infected orally with 1,000 embryonated T. canis eggs. A second group (n = 5), uninfected, was used as a control. Serum samples were collected for analysis on days 7, 14, 21, 28 and 60 post-infection (DPI). An indirect ELISA test was performed to evaluate the reactivity index (RI) of IgG anti-T. canis antibodies and to calculate the avidity index (AI). The animals showed seroconversion from the 14th DPI, with high AI (over 50%) except for one animal, which presented an intermediate AI. At 60 DPI, all the animals were seropositive and maintained a high AI. The data indicated that specific IgG antibodies formed early (14 DPI) in rabbits infected with T. canis, with a high avidity index that persisted throughout the course of the infection.
cris.boxmetadata.label.citationstartpage
99
cris.boxmetadata.label.citationendpage
104
cris.boxmetadata.label.volume
25
cris.boxmetadata.label.issue
1
cris.boxmetadata.label.language
English
cris.boxmetadata.label.ocdeknowledgeArea
Inmunología
Enfermedades infecciosas
Parasitología
cris.boxmetadata.label.subjects
cris.boxmetadata.label.doi
cris.boxmetadata.label.scopusidentifier
2-s2.0-84961901646
cris.boxmetadata.label.pubmedidentifier
cris.boxmetadata.label.source
Revista Brasileira de Parasitologia Veterinaria
cris.boxmetadata.label.containerissn
0103846X
peru-layout.shadow-copies
Directorio de Producción Científica
Scopus