Title
Detection of plasmid-mediated colistin resistance by colistin pre-diffusion and inhibition with EDTA test (CPD-E) in Enterobactereaceae
Date Issued
01 December 2019
Access level
metadata only access
Resource Type
journal article
Author(s)
Publisher(s)
Elsevier B.V.
Abstract
A phenotypic assay based on colistin pre-diffusion and differential inhibition of Mobile Colistin Resistance (MCR) protein activity by EDTA showed that, of the 92 strains tested, all MCR producers (49) exhibited an increase ≥5 mm in the inhibition zone around the area of pre-diffusion in the presence of EDTA, in comparison with colistin alone. Results suggest that CPD-E may differentiate MCR-producing microorganisms from resistant microorganisms without this marker.
Volume
167
Language
English
OCDE Knowledge area
Biología del desarrollo
Otros temas de Biología
Scopus EID
2-s2.0-85074155276
PubMed ID
Source
Journal of Microbiological Methods
ISSN of the container
01677012
Sponsor(s)
E.G.E is a PhD student at UBA under a fellowship from the PRONABEC , Ministerio de Educación , Perú (RJ N° 142 – 2017 -MINEDU-VMGI-PRONABEC-OBPOST). GG and JDC are members of CONICET. Grateful acknowledgment is made to Nilton Lincopan, Rafael Vignoli and Rafael Cantón for their generous contribution with mcr-2-, mcr-4- and mcr-5-harboring strains.
E.G.E is a PhD student at UBA under a fellowship from the PRONABEC, Ministerio de Educaci?n, Per? (RJ N? 142 ? 2017-MINEDU-VMGI-PRONABEC-OBPOST). GG and JDC are members of CONICET. Grateful acknowledgment is made to Nilton Lincopan, Rafael Vignoli and Rafael Cant?n for their generous contribution with mcr-2-, mcr-4- and mcr-5-harboring strains.
Sources of information:
Directorio de Producción Científica
Scopus