The present research, "Mathematical model to determine the mass transfer in the palm oil production process", also establishes the amount of palm oil in its extraction process. The industrialization of oil palm requires several stages in its production process: Sterilization, fruit processing, digestion, pressing, sieving, sedimentation, and drying; from the raw material to obtaining, by mechanical extraction, crude oil palm oil; In its different stages, there is mass transfer and energy transfer. The proposed methodology was based on the development of mathematical algorithms that allowed the simulation of the oil palm production process, mathematically representing the physical operations and the chemical processes intrinsic to it; The algorithms used in the model are based on the Law of Conservation of Mass and the Law of Conservation of Energy. The results obtained in the experimentation ratified the calculations of the proposed mathematical model that determined for 111.11 Kg of raw material (RFF), 24.45 Kg of crude palm oil are obtained.