Title
Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005
Date Issued
01 September 2008
Access level
metadata only access
Resource Type
journal article
Author(s)
Kochel T.
Aguilar P.
Comach G.
Alava A.
Vargas J.
Olson J.
Blair P.
Unidad de Investigación Médica Naval-6
Unidad de Investigación Médica Naval-6
Abstract
A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru. © 2008 Elsevier B.V.
Start page
682
End page
688
Volume
8
Issue
5
Language
English
OCDE Knowledge area
Bioquímica, Biología molecular
Virología
Epidemiología
Subjects
Scopus EID
2-s2.0-50649113938
PubMed ID
Source
Infection, Genetics and Evolution
ISSN of the container
15671348
Sponsor(s)
We thank Zonia Rios, Roxana Caceda and Carolina Guevara for invaluable technical support. This study was funded by the United States Department of Defense Global Emerging Infections Systems Research Program, WORK UNIT NUMBER: 847705.82000.25GB.B0016. The study protocol was approved by the Naval Medical Research Center Institutional Review Board (Protocols NMRCD.2000.0009 and NMRCD.2000.0006) in compliance with all applicable Federal regulations governing the protection of human subjects.
Sources of information:
Directorio de Producción Científica
Scopus