Title
Value of pretreatment automated hemogram as a 5-year survival predictor in uterine cervical cancer clinical stage IIB-IVA
Other title
[Valor del hemograma automatizado pretratamiento como predictor de sobrevida a 5 años en cáncer de cuello uterino estadio clínico IIB - IVA]
Date Issued
31 March 2021
Access level
open access
Resource Type
journal article
Author(s)
Hospital de Alta Complejidad Virgen de la Puerta
Publisher(s)
Medical Body of the Almanzor Aguinaga Asenjo National Hospital
Abstract
Objetive: To identify the value of the automated pretreatment blood count as a predictor of actuarial survival and 5-year disease-free actuarial survival in patients with clinical stage IIBIVA cervical cancer. Material and Methods: Analysis of survival that evaluated 48 patients with pathologic diagnosis of clinical stage IIB-IVA cervical cancer treated with chemoradiotherapy treated at the Medical Oncology service at the Virgen de la Puerta High Complexity Hospital during the period 2015-2017. Results: The mean age of the patients was 51.78 ± 12.06 years (Range: 32-77 years). The average tumor size was 5.55 ± 1.33 cm (Range: 3 - 9 cm). Regarding the clinical stage according to the FIGO classification, it was found that 77.7% was classified as stage IIB, 20.8% as IIIB and 2.1% had a diagnosis of stage IVA cervical cancer. Univariate analysis found that anemia, leukocytosis, thrombocytosis, neutrophil / lymphocyte index, neutrophilia, and high platelet / lymphocyte index are not predictors of 5-year actuarial survival (p> 0.05), in terms of disease-free survival at 5 years it was found that anemia, leukocytosis and pretreatment neutrophil / lymphocyte index showed a trend towards significance (p = 0.05-0.1) and pretreatment neutrophilia is a predictor of 5-year disease-free survival, being statistically significant (0% vs 38.9%, p = 0.026). Conclusion: Pretreatment neutrophilia (> 7,500 μL) is a prognostic factor for 5-year disease-free survival in patients with clinical stage IIB-IVA cervical cancer undergoing chemoradiotherapy.
Start page
40
End page
47
Volume
14
Issue
1
Language
Spanish
OCDE Knowledge area
Oncología Hematología
Scopus EID
2-s2.0-85119185181
Source
Revista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
ISSN of the container
22255109
Sources of information: Directorio de Producción Científica Scopus