Modeling and simulation of mechanical response of structures, relies on the use of computational models. Therefore, verification and validation procedures are the primary means of assessing accuracy, confidence and credibility in modeling. This paper is concerned with the validation of a three dimensional numerical model based on the finite element method suitable for the dynamic analysis of soil-structure interaction problems. The soil mass, structure, structure’s foundation and the appropriate boundary conditions can be represented altogether in a single model by using a direct approach. The theory of porous media of Biot is used to represent the soil mass as a two-phase material which is considered to be fully saturated with water; meanwhile other parts of the system are treated as one-phase materials. Plasticity of the soil mass is the main source of non-linearity in the problem and therefore an iterative-incremental algorithm based on the Newton- Raphson procedure is used to solve the nonlinear equilibrium equations. For discretization in time, the Generalized Newmark-β method is used. The soil is represented by a plasticity-based, effective-stress constitutive model suitable for liquefaction. Validation of the present numerical model is done by comparing analytical and centrifuge test results of soil and soil-pile systems with those results obtained with the present numerical model. A soil-pilestructure interaction problem is also presented in order to shown the potentiality of the numerical tool.