FAO in 2013 has launched a global campaign promoting the consumption of Quinoa, international demand increased rapidly, generating complex scenarios agri Aymara communities of the Titicaca watershed “main production worldwide Quinoa” with impacts on agricultural biodiversity system, in this context we consider important to investigate how it affects international demand, the intensification of production and export of Quinoa, Aymara system of agricultural biodiversity in the Lake Titicaca for which previously; (1) We determine the volumes of domestic production and export volumes from 2000 to 2015 in two major producers Peru and Bolivia, analyze its dynamics and differences, (2) show the changes in the Aymara system with the introduction of agro- biodiversity quinoa to the process of global economy; specifically the trend of conservation varieties of quinoa and maintenance of various agricultural species, also entered the situation of ancestral knowledge for growing quinoa and use of chemicals or synthetic fertilizers to increase productivity in the process of intensification and the extent of cultivation of Quinoa. In conclusion, the inclusion of quinoa in the free market economy and the intensive production model promoted by the government and the agricultural exporters, also legitimized by the majority of farmers in the study area, the intensification and expansion has reduced the many varieties of types of quinoa and the number of agricultural crop species in the same geographical area before quinoa for export as well as the extinction of ancestral knowledge and impoverishment of soils.