Title
Antimalarial activity and cytotoxicity of (-)-roemrefidine isolated from the stem bark of Sparattanthelium amazonum
Date Issued
01 January 1999
Access level
metadata only access
Resource Type
journal article
Author(s)
Inst. de Rech. pour le Developpemen
Publisher(s)
Georg Thieme Verlag
Abstract
(-)-Roemrefidine, an aporphine alkaloid isolated from Sparattanthelium amazonum Martius (Hernandiaceae) a vine from Bolivia, has been found to be active against both resistant and sensitive strains of Plasmodium falciparum in vitro and against P. berghei in mice. The compound demonstrated no cytotoxic activity against three cell lines (KB, HEp-2 and HeLa).
Start page
448
End page
449
Volume
65
Issue
5
Language
English
OCDE Knowledge area
Ciencias de las plantas, Botánica
Scopus EID
2-s2.0-0032994522
PubMed ID
Source
Planta Medica
ISSN of the container
00320943
Sources of information:
Directorio de Producción Científica
Scopus