This work aims to demonstrate the importance of coupling different degradation processes for the removal of the commercial herbicide Halosulfuron-Methyl (HSM). Using anode oxidation (AO) on boron-doped diamond as the base process; cathodically produced H2O2 (AO/H2O2), UV light (AO/UV), AO/UV/H2O2, electro-Fenton and photoelectron Fenton (PEF) are employed as hybrid processes for HSM degradation. All hybrid processes employed in the study exhibited synergism with AO, and the UV-irradiated processes presented an outstanding performance. In particular, the AO/UV/H2O2 process exhibited 90 % mineralization after 3 h of treatment, whereas the PEF process exhibited a complete removal of HSM after 45 min of treatment. In addition to the noticeable advantages of hybridization, the application of higher current densities is found to accelerate the degradation/mineralization of the compound of interest, although the process tends to be more energy demanding. In such a case, the use of a hybrid treatment process coupled to UV-irradiation allows one to mitigate this constraint while contributing toward obtaining higher mineralization degrees. The degradation/mineralization of more concentrated solutions is, however, found to occur more sluggishly under the treatment mechanisms investigated here, requiring longer times, although the process is noticeably more efficient in photo-irradiated processes, which recorded current efficiencies of above 100 %.