Title
Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation (Scientific Reports, (2017), 7, 1, (17762), 10.1038/s41598-017-17999-3)
Date Issued
01 December 2021
Access level
open access
Resource Type
corrigendum
Author(s)
Castillo E.
Abolhassani N.
Haruyama N.
Saito T.
Saido T.
Hokama M.
Iwaki T.
Ohara T.
Ninomiya T.
Kiyohara Y.
Sakumi K.
LaFerla F.M.
Nakabeppu Y.
Medical Institute of Bioregulation
Medical Institute of Bioregulation
Publisher(s)
Nature Research
Abstract
This article contains errors in the Introduction, where “AppNL-G-F/NL-G-F mice carrying the homozygous mutant App gene encoding the humanised Aβ sequence (G601R, F606Y, and R609H) with three pathogenic mutations, namely Swedish (KM595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G)10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age10,11.” should read: “AppNL-G-F/NL-G-F mice carrying the homozygous mutant App gene encoding the humanised Aβ sequence (G676R, F681Y, and R684H) with three pathogenic mutations, namely Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G)10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age10,11.” In addition, in the Methods section, under the subheading ‘Animals’, “Heterozygous App+/NL-G-F mice carrying humanised Aβ sequence (G601R, F606Y, R609H), Swedish (ML595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G) mutations, were previously established10.” should read: “Heterozygous App+/NL-G-F mice carrying humanised Aβ sequence (G676R, F681Y, R684H), Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G) mutations, were previously established10.”
Volume
11
Issue
1
Language
English
OCDE Knowledge area
Genética, Herencia Neurociencias
Scopus EID
2-s2.0-85114988066
PubMed ID
Source
Scientific Reports
ISSN of the container
20452322
DOI of the container
10.1038/s41598-021-97918-9
Sources of information: Directorio de Producción Científica Scopus