Title
Bayesian inference on multivariate-t nonlinear mixed-effects models for multiple longitudinal data with missing values
Date Issued
01 January 2018
Access level
metadata only access
Resource Type
journal article
Author(s)
Wang W.
Pontificia Universidad Católica de Chile
Publisher(s)
International Press of Boston, Inc.
Abstract
The multivariate-t nonlinear mixed-effects model (MtNLMM) has been shown to be a promising robust tool for analyzing multiple longitudinal trajectories following arbitrary growth patterns in the presence of outliers and possible missing responses. Owing to intractable likelihood function of the model, we devise a fully Bayesian estimating procedure to account for the uncertainties of model parameters, random effects, and missing responses via the Markov chain Monte Carlo method. Posterior predictive inferences for the future values and missing responses are also investigated. We conduct a simulation study to demonstrate the feasibility of our Bayesian sampling schemes. The proposed techniques are illustrated through applications to two case studies.
Start page
251
End page
264
Volume
11
Issue
2
Language
English
OCDE Knowledge area
Estadísticas, Probabilidad
Ciencias socio biomédicas (planificación familiar, salud sexual, efectos políticos y sociales de la investigación biomédica)
Subjects
Scopus EID
2-s2.0-85043349294
Source
Statistics and its Interface
ISSN of the container
19387989
Sponsor(s)
The authors would like to express their deepest gratitude to the Co-editor, the Associate editor and the reviewer for their insightful comments and suggestions that greatly improved this paper. W.L. Wang acknowledges the support of the Ministry of Science and Technology of Taiwan under Grant no. MOST 105-2118-M-035-004-MY2. L.M. Castro acknowledges support from Grant FONDECYT 1170258 and CONICYT-Chile through BASAL project CMM, Universidad de Chile
The authors would like to express their deepest gratitude to the Co-editor, the Associate editor and the reviewer for their insightful comments and suggestions that greatly improved this paper. W.L. Wang acknowledges the support of the Ministry of Science and Technology of Taiwan under Grant no. MOST 105-2118-M-035-004-MY2. L.M. Castro acknowledges support from Grant FONDECYT 1170258 and CONICYT-Chile through BASAL project CMM, Uni-versidad de Chile.
Sources of information:
Directorio de Producción Científica
Scopus