Methanol is a highly toxic alcohol present in many solvents and also as part of handmade or illicit alcohols. Oral ingestion occurs after accidental or suicidal events or as part of alcoholism and can be potentially fatal if not diagnosed and treated promptly. Patients who survive may develop parkinsonism or a mixture of pyramidal and extrapyramidal signs. Those with necrotic putaminal lesions may be at higher risk of developing parkinsonism. We present two cases of acute methanol intoxication followed by blindness and acute parkinsonism.