The aim of this study was to assess the individual and grouped influence of host-related factors on dental caries experience in permanent dentition of 7-9 year-old children. One hundred and twenty one children were recruited applying a stratified cluster sampling without replacement. Clinical examinations, Colorimetric Test and non-stimulated and stimulated saliva collection were performed; the samples obtained were later incubated using Snyder culture medium. Simple and multiple binary logistic regression analyses were performed to assess the individual and grouped influence of the host-related factors and establish a modelfor predicting dental caries in permanent dentition. 78.5% of the evaluated children presented dental caries in permanent dentition. Binary logistic regression analyses revealMd that only dental caries in deciduous dentition and stimulated salivary flow were significantly associated to dental caries in permanent dentition. The final multivariate model showed that the adjusted OR was 1.76 for an increase of 1 tooth in dmft and 2.29 for a decrease of 1 ml in stimulated salivary flow. Dental caries in deciduous dentition is a risk indicator for dental caries in permanent dentition, and stimulated salivary flow is a protective factor Variables like enamel resistance to acid dissolution and buffer capacity are not related to dental caries in permanent dentition, making them inappropriate for risk studies.