Title
Watching single RNA molecules respond to local application of mechanical force
Date Issued
01 December 2002
Access level
metadata only access
Resource Type
conference paper
Author(s)
University of California
Abstract
In 1997, C. Jarzynski proved an equality relating the irreversible work to the equilibrium free energy difference, ΔG. In particular, Jarzynski stated that it is possible to obtain equilibrium thermodynamic parameters from processes carried out arbitrarily far from equilibrium. Jarzynski's equality was tested by mechanically stretching a single molecule of RNA reversibly and irreversibly between two conformations. It was found that it is possible to recover the equilibrium ΔG profile of the stretching process from the nonequilibrium experiments.
Start page
595
Volume
1
Language
English
OCDE Knowledge area
Bioquímica, Biología molecular
Biofísica
Scopus EID
2-s2.0-0036912340
ISSN of the container
05891019
Conference
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings - Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
Sources of information:
Directorio de Producción Científica
Scopus