Participatory research (PR) has been presented as an alternative to develop sustainable agricultural technologies more responsive to farmer needs. However, the institutionalization of PR methods is influenced by stakeholders' perceptions about incentives and disincentives. The study was conducted by gathering and analysing information from farmers, facilitators and institutional representatives involved in conducting potato-related PR in Bolivia, Ethiopia, Peru and Uganda between 2005 and 2007. Results indicate that at the farmer level the most important incentives are related to the benefits they can acquire (improving human and social capital, which is essential for more sustainable results). At the facilitator level, operational and organizational factors represent incentives, for example, perception of additional benefits, existing capabilities and skills, and access to logistic support. Some factors also represent disincentives such response to different types of demands, and instability of jobs within institutions. At the organization level, both financial and operational factors represent incentives or disincentives, such as the cost of PR methods, availability of skillful human resources, quality of technologies generated and the sustainability of financial support. These factors at both individual and organizational level need to be taken into consideration by organizations aiming at scaling up and out-of-PR methods and derived technologies in a sustainable way. © 2011 Earthscan.