Title
Modulation of the cognitive event-related potential P3 by transcranial direct current stimulation: Systematic review and meta-analysis
Date Issued
01 January 2022
Access level
metadata only access
Resource Type
review
Author(s)
Publisher(s)
Elsevier Ltd
Abstract
Transcranial direct current stimulation (tDCS) has been widely used to modulate cognition and behavior. However, only a few studies have been probing the brain mechanism underlying the effects of tDCS on cognitive processing, especially throughout electrophysiological markers, such as the P3. This meta-analysis assessed the effects of tDCS in P3 amplitude and latency during an oddball, n-back, and Go/No-Go tasks, as well as during emotional processing. A total of 36 studies were identified, but only 23 were included in the quantitative analysis. The results show that the parietal P3 amplitude increased during oddball and n-back tasks, mostly after anodal stimulation over the left dorsolateral prefrontal cortex (p = 0.018, SMD = 0.4) and right inferior frontal gyrus (p < 0.001, SMD = 0.669) respectively. These findings suggest the potential usefulness of the parietal P3 ERP as a marker of tDCS-induced effects during task performance. Nonetheless, this study had a low number of studies and the presence of considerable risk of bias, highlighting issues to be addressed in the future.
Start page
894
End page
907
Volume
132
Language
English
OCDE Knowledge area
Neurología clínica
Neurociencias
Subjects
Scopus EID
2-s2.0-85119208105
PubMed ID
Source
Neuroscience and Biobehavioral Reviews
ISSN of the container
01497634
Sponsor(s)
AJM and AL are supported by the Portuguese Foundation for Science and Technology and the Portuguese Ministry of Science, Technology and Higher Education through national funds, and co-financed by FEDER through COMPETE2020under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007653). KPB is supported by the Spaulding Research Institute Accelerator grant (2020A015281). FF is supported by the National Institute of Health (NIH) grant R01 AT009491-01A1. SC was supported by the Portuguese Foundation for Science and Technology and the Portuguese Ministry of Science, through national funds and co-financed by FEDER through COMPETE2020 under the PT2020 Partnership Agreement (POCI-01−0145-FEDER-007,653) and along with OFG and JL were also funded through the grants: PTDC/PSI-ESP/30280/2017 and PTDC/PSI-ESP/29701/2017.
Sources of information:
Directorio de Producción Científica
Scopus