Title
Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
Date Issued
01 January 2022
Access level
metadata only access
Resource Type
journal article
Author(s)
Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas
Publisher(s)
John Wiley and Sons Inc
Abstract
The present study describes the novel development and application of an ivermectin (IVM) sensing electrochemical platform based on reduced graphene oxide (rGO) and the macrocyclic host β-cyclodextrin (β-CD) molecule. The sensing method was based in the host-guest characteristics of β-CD and competitive interaction between the target analyte and the methylene blue (MB) redox probe. Differential pulse voltammetry (DPV) was employed for the detection of IVM and a linear response between 0.5 and 40.0 μmol L−1 with a limit of detection of 0.25 μmol L−1 was obtained using the glassy carbon (GC)/rGO/β-CD electrode. The sensing platform was successfully applied for the detection of IVM in tap water samples, which may expand the applications of β-CD towards the analysis of other chemical species.
Language
English
OCDE Knowledge area
Electroquímica
Subjects
Scopus EID
2-s2.0-85131013655
Source
Electroanalysis
ISSN of the container
10400397
Source funding
Sponsor(s)
This research received funding from PROCIENCIA (grant 006-2020-FONDECYT-BM) and FAPESP (grant 2017/24274-3). The authors also would like to acknowledge the research grant (301192/2019-7) awarded by CNPq and the LMA-IQ for the availability of using the scanning electron microscope.
Sources of information:
Directorio de Producción Científica
Scopus