breast cancer (BC) is the leading cause of death secondary to malignancy in women. It ranks third in mortality in women in reproductive age, produced by non-modifiable (genetic and hormonal) and modifiable factors. Our objective was to describe and analyze the epidemiological characteristics of deaths from BC in the State of Mexico. of 273 verbal autopsies, the most common age (23.07 %) was between 40 and 49 years. The educational level of schooling were complete elementary school (20.51 %), incomplete elementary school (19.04 %) and complete high school (13.91 %). the institution with the highest number of patients was the Instituto Mexicano del Seguro Social with 139 (50.91 %). The towns with a higher frequency were Malinalco, Ayapango, Atizapán, Zacualpan and Apaxco. The Mortality was higher in Valle de Bravo, Coatepec Harinas and Toluca. the increase in BC has permitted the emergence of a new hypothesis known as endocrine disruption, according to this premise, this results from exposure to chemicals introduced into the environment by human activity capable of altering the hormonal balance.