The productive performance of broilers supplemented with tylosin phosphate and enramycin as growth promoters up to 42 days of age was evaluated. Four hundred male broilers were distributed into 4 treatments of 100 birds with 5 repetitions each. The treatments were: T1, control; diet without antibiotic; T2, diet with 8% enramycin in a dose of 10 ppm; T3, diet with enramycin 8% in a dose of 5 ppm; T4, diet with tylosin phosphate 25% in a dose of 55 ppm. The treated groups presented a higher body weight and better feed conversion index and European productive efficiency index than the control group; however, there were no differences in body weight gain, feed intake and mortality.