Title
Evidence for balancing selection at the DAB locus in the axolotl, Ambystoma mexicanum
Date Issued
01 December 2007
Access level
metadata only access
Resource Type
journal article
Author(s)
Richman A.D.
Herrera G.
Reynoso V.H.
Méndez G.
Zambrano L.
Abstract
The axolotl (Ambystoma mexicanum) has been characterized as immunodeficient, and the absence of major histocompatibility complex (MHC) class II polymorphism has been cited as a possible explanation. Here we present evidence for considerable allelic polymorphism at the MHC class II DAB locus for a sample of wild-caught axolotls. Evidence that these sequences are the product of balancing selection for disease resistance is discussed. © 2007 The Authors.
Start page
475
End page
478
Volume
34
Issue
6
Language
English
OCDE Knowledge area
Genética, Herencia
Zoología, Ornitología, Entomología, ciencias biológicas del comportamiento
Scopus EID
2-s2.0-36248967017
PubMed ID
Source
International Journal of Immunogenetics
ISSN of the container
1744313X
Sources of information:
Directorio de Producción Científica
Scopus