Title
Identificación de células proliferativas en quistes de Taenia solium
Other title
Identification of proliferating cells in Taenia solium cysts
Date Issued
01 January 2014
Access level
metadata only access
Resource Type
journal article
Publisher(s)
Instituto Nacional de Salud
Abstract
Neoblasts are totipotent cells, solely responsible for the proliferation and maturation of tissues in free-living flatworms. Similar cells have been isolated from parasitic flatworms such as Echinococcus. Taenia solium causes human taeniasis (intestinal) and cysticercosis in humans and pigs. Brain infection with larvae (cysts) of T. solium results in neurocysticercosis which is hyperendemic in Peru, and its treatment is associated with serious neurological symptoms. The proliferative capacity and development stages of T. solium have not been described and the neoblasts of this parasite have not been characterized We looked for cell proliferation in T. solium cysts collected from an infected pig, which were identified when replicating and incorporating bromodeoxyuridine nucleotide detected with a monoclonal antibody. A stable cell line of neoblasts would be useful for systematic in vitro studies on drug efficacy and the biology of T. solium.
Start page
702
End page
706
Volume
31
Issue
4
Language
Spanish
OCDE Knowledge area
Parasitología Neurología clínica
Scopus EID
2-s2.0-84920943897
PubMed ID
Source
Revista Peruana de Medicina Experimental y Salud Publica
ISSN of the container
17264634
Sources of information: Directorio de Producción Científica Scopus