This paper contains information about the hunting, abundance and the hunting impact of the mammals that inhabit the lowland forests of the area surrounding two communities in the interior of the Pacaya Samiria National Reserve. It is based on hunting records and transect censuses. Hunting records show an average annual harvest of 190,3 mammals in the San Miguel area, equivalent to 2,275,9 kg of bushmeat; and 104,5 mammals in the Parinari area, equivalent to 985,9 kg of bushmeat. Primates were abundant in both study areas; however, the estimated densities were much higher in the Parinari area. No ungulates species were observed in the San Miguel area, whilst in the Parinari area the density of tapir (Tapirus terrestris Linnaeus) was estimated at 0,2 individuals/ km2 and that of white lipped peccary (Tayassu pecari Link) at 6, 6 individuals/km2. Finally, the harvest model suggests overhunting of the tapir, white bellied spider monkey (Ateles belzebuth E. Geoffroy), common wooly monkey (Lagothrix lagotricha Humboldt) and red howler monkey (Alouatta seniculus Linnaeus), for which harvest in some cases reached 100% of the production. We discuss the factors that should influence the scarcity and/or absence of some species, particularly ungulates and primates.