This research article presents a comparative study between two design alternatives of an anti-wear plate fastening system used in transfer chutes of the mining industry. The mechanical behavior of the fastening system is analyzed while considering the influence of the anti-wear plate thickness. For this purpose, finite element numerical simulation is used, including its experimental validation. The results reveal that the antiwear plate can reach a remaining thickness of 7.5 mm in alternative 1 and 12 mm in alternative 2, considering a safety factor of 1.5. Both alternatives perform better than the current design available, where the anti-wear plate is removed with a thickness of 15 mm due to fastening system limitations. It is concluded that alternative 1 is the best option proposed here since it allows to extending the life of the anti-wear plate by 20%.