Title
Automatic classification of pediatric pneumonia based on lung ultrasound pattern recognition
Date Issued
2018
Access level
open access
Resource Type
journal article
Publisher(s)
Public Library of Science
Abstract
Pneumonia is one of the major causes of child mortality, yet with a timely diagnosis, it is usually curable with antibiotic therapy. In many developing regions, diagnosing pneumonia remains a challenge, due to shortages of medical resources. Lung ultrasound has proved to be a useful tool to detect lung consolidation as evidence of pneumonia. However, diagnosis of pneumonia by ultrasound has limitations: it is operator-dependent, and it needs to be carried out and interpreted by trained personnel. Pattern recognition and image analysis is a potential tool to enable automatic diagnosis of pneumonia consolidation without requiring an expert analyst. This paper presents a method for automatic classification of pneumonia using ultrasound imaging of the lungs and pattern recognition. The approach presented here is based on the analysis of brightness distribution patterns present in rectangular segments (here called “characteristic vectors“) from the ultrasound digital images. In a first step we identified and eliminated the skin and subcutaneous tissue (fat and muscle) in lung ultrasound frames, and the “characteristic vectors”were analyzed using standard neural networks using artificial intelligence methods. We analyzed 60 lung ultrasound frames corresponding to 21 children under age 5 years (15 children with confirmed pneumonia by clinical examination and X-rays, and 6 children with no pulmonary disease) from a hospital based population in Lima, Peru. Lung ultrasound images were obtained using an Ultrasonix ultrasound device. A total of 1450 positive (pneumonia) and 1605 negative (normal lung) vectors were analyzed with standard neural networks, and used to create an algorithm to differentiate lung infiltrates from healthy lung. A neural network was trained using the algorithm and it was able to correctly identify pneumonia infiltrates, with 90.9% sensitivity and 100% specificity. This approach may be used to develop operator-independent computer algorithms for pneumonia diagnosis using ultrasound in young children. © 2018 Correa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Volume
13
Issue
12
Number
47
Language
English
Scopus EID
2-s2.0-85058064971
PubMed ID
Source
PLoS ONE
ISSN of the container
1932-6203
Sponsor(s)
This work was supported by Grand Challenges Canada; grant number: 0542-01-10, Grand Challenges Canada; grant number: 0688-01-10 URL: www.grandchallenges.ca, National Institutes of Health; grant number: 1D43TW009349-03 URL: https://www.nih.gov, CONCYTEC-FONDECIT; grant number: 054-2014 URL: https://portal.concytec.gob.pe, PUCP-DGI; grant number: 70242-2149 URL: http://www.pucp. edu.pe. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Sources of information: Directorio de Producción Científica