Title
Simulating the Arnaoutova-Kleinman Model of Tubular Formation at Angiogenesis Events Through Classical Electrodynamics
Date Issued
01 January 2022
Access level
metadata only access
Resource Type
conference paper
Publisher(s)
Springer Science and Business Media Deutschland GmbH
Abstract
The Arnaoutova-Kleinman model is simulated in an entire scenario of Classical Electrodynamics. For this end the 4-steps are considered: (i) The migration of endothelial cells, (ii) the random attachment among them, (iii) the apparition of bFGF proteins generating electrical and lines fields, and (iv) the tubule formation from these proteins. Simulations have shown that tubule formation as the one of the first phases of Angiogenesis would require large values of electric field and a fast adhesion of bFGF proteins to produce stable lines of electric field. On the other hand, tubular formation can also be stopped through external fields that might cancel the adhesion of proteins. Therefore prospective nano devices would play a relevant role to avoid first phases of tumor formation.
Start page
248
End page
254
Volume
506 LNNS
Language
English
OCDE Knowledge area
Ingeniería eléctrica, Ingeniería electrónica Oncología
Scopus EID
2-s2.0-85135082313
Source
Lecture Notes in Networks and Systems
ISSN of the container
23673370
ISBN of the container
9783031104602
Conference
Computing Conference, 2022
Sources of information: Directorio de Producción Científica Scopus