Title
Evaluation of multiple open-source deep learning models for detecting and grading COVID-19 on chest radiographs
Date Issued
01 November 2021
Access level
open access
Resource Type
journal article
Author(s)
Publisher(s)
SPIE
Abstract
Purpose: Chest x-rays are complex to report accurately. Viral pneumonia is often subtle in its radiological appearance. In the context of the COVID-19 pandemic, rapid triage of cases and exclusion of other pathologies with artificial intelligence (AI) can assist over-stretched radiology departments. We aim to validate three open-source AI models on an external test set. Approach: We tested three open-source deep learning models, COVID-Net, COVIDNet-S-GEO, and CheXNet for their ability to detect COVID-19 pneumonia and to determine its severity using 129 chest x-rays from two different vendors Phillips and Agfa. Results: All three models detected COVID-19 pneumonia (AUCs from 0.666 to 0.778). Only the COVID Net-S-GEO and CheXNet models performed well on severity scoring (Pearson's r 0.927 and 0.833, respectively); COVID-Net only performed well at either task on images taken with a Philips machine (AUC 0.735) and not an Agfa machine (AUC 0.598). Conclusions: Chest x-ray triage using existing machine learning models for COVID-19 pneumonia can be successfully implemented using open-source AI models. Evaluation of the model using local x-ray machines and protocols is highly recommended before implementation to avoid vendor or protocol dependent bias.
Volume
8
Issue
6
Language
English
OCDE Knowledge area
Sistema respiratorio
VirologĂa
Subjects
Scopus EID
2-s2.0-85122634852
Source
Journal of Medical Imaging
ISSN of the container
23294302
Source funding
Manchester Biomedical Research Centre
Sponsor(s)
Research reported in this publication was supported by Realize, Inc. and IntriHEALTH Ltd. The authors would like to thank Jeffrey Swartzberg and Susan Otto for providing the radiological interpretations of the x-rays, Cimar UK Ltd. for help with image anonymization and exchange, and Eric Hart for providing helpful feedback on the initial study design. D. W. D is partly supported by the NIHR Manchester Biomedical Research Centre. Author contributions: Guarantor of integrity of entire study, A. R.; study concepts/study design, all authors; data acquisition, M. T. and A. R.; data analysis/interpretation, all authors; statistical analysis, A. R.; literature research, all authors; manuscript drafting, A. R. and D. W. D.; manuscript revision for important intellectual content, all authors; and approval of final version of submitted manuscript, all authors.
Sources of information:
Directorio de ProducciĂ³n CientĂfica
Scopus