Many Western democracies have implemented multiculturalism to integrate different minority groups, including immigrants. What happens with countries that are recently experiencing an increasing growth in their immigration rates? This is the case of Chile. As a consequence of continuing economic growth, it has become an attractive destination to people from neighbouring nations. Among these immigrants, Peruvians are the largest group. Since in Chile multiculturalism has started to become an issue of public opinion, the current study analyzed levels of endorsement of multiculturalism and differences in Socioeconomic Status (SES) among Chileans (N= 300) and Peruvian immigrants (N= 400). Based on the Instrumental Model of Group Conflict and Social Identity Theory, we tested predictors of multiculturalism. In addition, we analyzed the relationship between acculturation and intergroup variables in both samples. Findings showed Chilean endorsement of multiculturalism. This was negatively associated with perceived threat and Social Dominance Orientation, especially among people of low SES. Moreover, permeability and legitimacy proposed by Social Identity Theory emerged as important predictors of desire for separation among Peruvian immigrants. These results are discussed in terms of its conceptual and public policy implications in Chile. © 2013 Elsevier Ltd.